{"id":269,"date":"2023-02-17T17:00:00","date_gmt":"2023-02-17T17:00:00","guid":{"rendered":"https:\/\/maleexcel.com\/newblog\/?p=269"},"modified":"2025-03-20T20:39:43","modified_gmt":"2025-03-20T20:39:43","slug":"is-it-safe-to-take-ed-meds-and-trt-together","status":"publish","type":"post","link":"https:\/\/maleexcel.com\/blog\/hormone-replacement-therapy\/is-it-safe-to-take-ed-meds-and-trt-together\/","title":{"rendered":"Is it Safe to Take ED meds and TRT Together?"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\" id=\"h-can-you-take-viagra-or-cialis-with-trt\">Can You Take Viagra or Cialis with TRT?<\/h2>\n\n\n\n<p>The simple answer to the question is it safe to <a href=\"https:\/\/maleexcel.com\/blog\/erectile-dysfunction\/what-are-the-best-ed-meds\/\">take ED meds<\/a> and TRT together? Is yes. ED meds and testosterone combined offer an excellent solution for guys with ED and symptoms of low T.<\/p>\n\n\n\n<p>ED meds:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Offer relief from erectile dysfunction <\/li>\n\n\n\n<li>Improves oxygen flow around the body<\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<p>TRT:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Increase sexual desire and energy levels<\/li>\n\n\n\n<li>Relieve many of the symptoms of low testosterone associated with ED<\/li>\n\n\n\n<li>Increase nitric oxide production, making it easier to become erect<\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-what-s-the-connection-between-testosterone-and-erections\">What&#8217;s the Connection Between Testosterone and Erections?<\/h2>\n\n\n\n<p>Testosterone replacement significantly <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5649360\/\" rel=\"noreferrer noopener\" target=\"_blank\">increases sexual desire<\/a><sup>1<\/sup> and can improve responsiveness to ED medications. However, ED meds alone will not increase libido. They only increase blood flow to the penis and can be ineffective without mental or physical stimulation.<\/p>\n\n\n\n<p>If you experience erectile dysfunction and medications, such as Viagra\u00ae, don&#8217;t work as well as you had hoped, don&#8217;t worry. Other options available could improve your sexual function and benefit other areas of your overall health.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-can-low-testosterone-cause-ed\">Can Low Testosterone Cause ED?<\/h2>\n\n\n\n<p>Low testosterone alone may not directly cause ED, but ED is a common symptom for those with low T. It&#8217;s&nbsp;clear that low testosterone levels are related to many chronic conditions that play a role in erectile dysfunction<\/p>\n\n\n\n<div class=\"wp-block-group is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-columns cta1 is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:30%\">\n<div class=\"wp-block-group is-layout-constrained wp-block-group-is-layout-constrained\">\n<figure class=\"wp-block-image aligncenter size-full is-style-rounded\"><img fetchpriority=\"high\" decoding=\"async\" width=\"280\" height=\"280\" src=\"https:\/\/static.maleexcel.com\/wp-content\/uploads\/sites\/12\/2023\/06\/02142946\/Heart-with-hands-.webp\" alt=\"Heart hands\" class=\"wp-image-2632\" srcset=\"https:\/\/static.maleexcel.com\/wp-content\/uploads\/sites\/12\/2023\/06\/02142946\/Heart-with-hands-.webp 280w, https:\/\/static.maleexcel.com\/wp-content\/uploads\/sites\/12\/2023\/06\/02142946\/Heart-with-hands--150x150.webp 150w\" sizes=\"(max-width: 280px) 100vw, 280px\" \/><\/figure>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center cta1-content-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:70%\">\n<p class=\"has-text-align-center has-large-font-size\"><strong>Symptoms of Low T? See if TRT Can Help<\/strong><\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill\"><a class=\"wp-block-button__link has-vivid-cyan-blue-background-color has-background wp-element-button\" href=\"https:\/\/go.maleexcel.com\/hormone-assessment\/ghrt\" target=\"_blank\" rel=\"noreferrer noopener\">Take the Hormone Assessment<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-symptoms-of-low-t-that-can-cause-erectile-dysfunction\"><strong>Symptoms of low T that can cause erectile dysfunction:<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Type 2 diabetes<\/li>\n\n\n\n<li>Loss of libido<\/li>\n\n\n\n<li>Obesity and visceral fat<\/li>\n\n\n\n<li>Depression<\/li>\n\n\n\n<li>Metabolic syndrome<\/li>\n\n\n\n<li>Atherosclerosis (clogged arteries)<\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<p>These conditions are common risk factors that restrict blood flow to the penis, making it more challenging to get erect. If you suffer from any of these, it&#8217;s certainly worth taking our <a href=\"https:\/\/go.maleexcel.com\/hormone-assessment\/shrt1\" target=\"_blank\" rel=\"noreferrer noopener\">free assessment<\/a> to see if TRT could help.<\/p>\n\n\n\n<p>Guys with <a href=\"https:\/\/maleexcel.com\/blog\/weight-loss\/can-you-take-semaglutide-and-testosterone-together\/\">lower testosterone tend to gain weight<\/a>, lose muscle definition, and suffer from a lack of energy and libido. As a result, it can severely dent a man&#8217;s sexual confidence and desire to have sex. Erectile function is also affected by your mental state, which can have devastating effects on your ability to become aroused.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-erectile-dysfunction-could-indicate-cardiovascular-problems\">Erectile Dysfunction Could Indicate Cardiovascular Problems.<\/h2>\n\n\n\n<p>ED can be <a href=\"https:\/\/maleexcel.com\/blog\/erectile-dysfunction\/what-causes-erectile-dysfunction-e-d\/\">a symptom of cardiovascular disease<\/a> (heart disease). One early indicator of heart disease is a condition called endothelial dysfunction. This disorder stops blood vessels from dilating (opening) properly. Often affecting the blood vessels in the penis, endothelial dysfunction could be the first hint that something isn&#8217;t right. It could also indicate the beginnings of heart disease.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-erectile-dysfunction-and-diabetes\"><strong>Erectile Dysfunction and Diabetes<\/strong><\/h3>\n\n\n\n<p>High blood sugar levels associated with type 2 diabetes can damage blood vessels and nerves responsible for gaining an erection. Two particular studies highlight how low T and diabetes are linked. The <a href=\"https:\/\/www.nature.com\/articles\/ijir20101#:~:text=Diabetes%20is%20one%20of%20the,varies%20from%2035%20to%2090%25.\" rel=\"noreferrer noopener\" target=\"_blank\">first<\/a><sup>2<\/sup>&nbsp;shows how prevalent ED is amongst those with low T. The second <a href=\"https:\/\/academic.oup.com\/jcem\/article\/93\/5\/1834\/2598879\" rel=\"noreferrer noopener\" target=\"_blank\">study<sup>3<\/sup> <\/a>observed 580 men and revealed fascinating facts about ED, testosterone, and men with type 2 diabetes.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Diabetes is one of the most common comorbidities of ED.  <\/li>\n\n\n\n<li>ED among diabetic men varies from 35 to 90%.<\/li>\n\n\n\n<li>Forty-three percent of men with type 2 diabetes had reduced total testosterone<\/li>\n\n\n\n<li>57% of men with type 2 diabetes have reduced free testosterone.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-does-trt-help-erectile-dysfunction\">Does TRT Help Erectile Dysfunction?<\/h2>\n\n\n\n<p>Testosterone levels <a href=\"https:\/\/maleexcel.com\/blog\/erectile-dysfunction\/can-testosterone-help-erectile-dysfunction\/\">can impact aspects of health that can cause ED<\/a>. Before the days of Viagra\u00ae and Cialis\u00ae, many doctors would prescribe TRT as a &#8216;go-to&#8217; treatment for ED. TRT as an ED treatment makes sense. Notably, testosterone is at the core of sexual arousal, the desire for sex and some specific mechanics of getting an erection.<\/p>\n\n\n\n<p>Without getting too technical, testosterone helps your body release an enzyme called nitric oxide. This chemical helps relax blood vessels meaning blood can flow freely into the penis. Many men with ED also have atherosclerosis (hardened arteries). If your arteries become hardened, it becomes difficult for nitric oxide to relax the blood vessels. Unfortunately, men with low T tend not to produce enough nitric oxide, which makes it harder to get hard. This response is particularly significant because ED drugs like Viagra and Cialis are less effective if nitric oxide is low. So, for those with low T, ED meds may be less effective or not work at all.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Testosterone is essential for erections and male sexual behavior and attitudes.<\/li>\n\n\n\n<li>Testosterone replacement therapy (TRT) in hypogonadal patients with ED should be the first treatment considered.<\/li>\n\n\n\n<li>TRT alone might not be adequate in all cases of ED because of the many cause of the disorder<\/li>\n\n\n\n<li>In these cases, combination therapy with ED medication might improve outcomes.<\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<p>Take our free assessment to see if testosterone could help reignite your sex life.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-combining-testosterone-and-erectile-dysfunction-treatments-may-improve-results\">Combining Testosterone and Erectile Dysfunction Treatments May Improve Results<\/h2>\n\n\n\n<p>For some guys with low testosterone, TRT can restore erectile function without needing ED meds. <a href=\"https:\/\/maleexcel.com\/blog\/erectile-dysfunction\/what-is-erectile-dysfunction-medication\/\">Taking ED meds<\/a> and TRT together helps those who don&#8217;t respond to one single treatment.<\/p>\n\n\n\n<p>If you take <a href=\"https:\/\/maleexcel.com\/blog\/erectile-dysfunction\/get-ed-meds-online\/\">ED meds and TRT Together<\/a>, especially for those with type 2 diabetes, vascular disease, and obesity, it can target many causes of ED. Many men can reverse some of these causes with long-term testosterone treatment and lifestyle changes. Interestingly, <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6036338\/\" target=\"_blank\" rel=\"noreferrer noopener\">studies<sup>4<\/sup><\/a> even show that Sildenafil (Generic Viagra\u00ae) helps increase testosterone levels in men via direct action on the testes.<\/p>\n\n\n\n<p>Using PDE5 inhibitors such as Viagra\u00ae or Cialis\u00ae with testosterone is typically safe for men with low T and ED. Our providers at Male Excel often prescribe both to benefit sexual and overall health. Significantly, TRT can relieve symptoms of low T, such as low energy, low libido, and even weight and cardiovascular problems. ED medications can increase blood flow to the penis; studies now show it may improve pulmonary hypertension. Crucially, strong evidence5 shows that combining these treatments may benefit men with both low T and ED.<\/p>\n\n\n\n<div class=\"wp-block-group is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-columns cta1 is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:30%\">\n<div class=\"wp-block-group is-layout-constrained wp-block-group-is-layout-constrained\">\n<figure class=\"wp-block-image aligncenter size-full\"><img decoding=\"async\" width=\"1024\" height=\"504\" src=\"https:\/\/static.maleexcel.com\/wp-content\/uploads\/sites\/12\/2023\/04\/25092026\/man-holding-belly-CTA.png\" alt=\"man holding belly\" class=\"wp-image-2450\" srcset=\"https:\/\/static.maleexcel.com\/wp-content\/uploads\/sites\/12\/2023\/04\/25092026\/man-holding-belly-CTA.png 1024w, https:\/\/static.maleexcel.com\/wp-content\/uploads\/sites\/12\/2023\/04\/25092026\/man-holding-belly-CTA-300x148.png 300w, https:\/\/static.maleexcel.com\/wp-content\/uploads\/sites\/12\/2023\/04\/25092026\/man-holding-belly-CTA-768x378.png 768w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column cta1-content-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:70%\">\n<h2 class=\"wp-block-heading has-text-align-center\" id=\"h-how-you-feel-tomorrow-starts-today\">   How you feel tomorrow starts today! <\/h2>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-background wp-element-button\" href=\"https:\/\/go.maleexcel.com\/hormone-assessment\/ghrt\" style=\"border-radius:8px;background-color:#9c0c19\">Take Assessment<\/a><\/div>\n\n\n\n<div class=\"wp-block-button is-style-outline is-style-outline--1\"><a class=\"wp-block-button__link has-text-color wp-element-button\" href=\"https:\/\/maleexcel.com\/free-hrt-consult\/?\" style=\"border-radius:8px;color:#9c0c19\">Schedule Free Consult<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>ED medications like Viagra or Cialis, combined with testosterone replacement therapy (TRT), can effectively treat erectile dysfunction and low testosterone symptoms. This combination has no adverse reactions and is considered perfectly safe.  Many physicians advise men to take ED meds and TRT together due to having a host of health benefits. <\/p>\n","protected":false},"author":17,"featured_media":2478,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[45,44,47],"tags":[],"class_list":["post-269","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-erectile-dysfunction","category-hormone-replacement-therapy","category-testosterone"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.5 (Yoast SEO v26.5) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Is it Safe to Take ED meds and TRT Together? - Blog Male Excel<\/title>\n<meta name=\"description\" content=\"Is it Safe to Take ED meds and TRT Together? 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