Quick Summary
- Testosterone supports strength, mood, libido, and energy levels, which naturally decline with age.
- ZMA combines zinc, magnesium aspartate, and vitamin B6, nutrients linked to hormone balance and recovery.
- Zinc supports testosterone production and immune health; magnesium helps with sleep and stress response.
- Safe doses are around 30 mg zinc, 450 mg magnesium, and 10.5 mg B6.
- ZMA is best taken on an empty stomach before bed for better absorption and sleep benefits.
- It's not a magic testosterone booster, but it may help fill nutritional gaps that affect hormone levels.
Testosterone is involved in many areas of men's health. It supports muscle growth, mood regulation, energy levels, and reproductive function. With age, testosterone levels can start to decline naturally. This often causes fatigue, lower libido, and reduced strength.
To address these changes, many people explore ways to support testosterone production. One common approach is taking supplements. Among the many options available, ZMA provides high-dose zinc supplements.
So, does ZMA increase testosterone? Research shows mixed results. However, among athletes, ZMA is typically positioned as a product that, due to its claims, supports testosterone production and improvement in exercise performance. While ZMA is not a magic fix, it may help those with low zinc or magnesium levels.
This blog aims to examine whether ZMA can influence testosterone levels and whether it might help raise testosterone, especially for those who need the support.

What Is ZMA?
ZMA is a popular dietary supplement comprising three nutrients: zinc, magnesium aspartate, and vitamin B6. These three components are often grouped because they support several key functions in the body.
Zinc is a trace element that affects immune response, hormone production, and protein metabolism. It helps the body make proteins and supports wound healing. Many people don't get enough zinc, especially if their diet lacks variety. Consequently, low levels can affect testosterone and immune function.
Magnesium is another essential micronutrient. It supports muscle relaxation, nerve function, and sleep quality. The form used in ZMA is magnesium aspartate, which has a better absorption rate than other types. You can experience fatigue, poor sleep, and muscle cramps if you are magnesium deficient.
Vitamin B6 supports brain function and enables the body to use energy extracted from food. It also plays a part in how the body processes amino acids, which are the building blocks of protein.
When combined, zinc and magnesium work together to support recovery, sleep, and hormone balance. This is why ZMA is often taken at night. The idea is that the body uses these nutrients more effectively during rest.
The zinc magnesium aspartate blend is believed to benefit people who train hard or experience high stress. These groups often lose more zinc and magnesium through sweat and increased physical demand. Consuming ZMA supplements helps restore those losses.
It is important to remember that these supplements are not meant to replace a healthy diet but can fill specific gaps.
Effects of ZMA on Testosterone Levels
ZMA is often used to support testosterone production, especially among men looking to improve recovery, sleep, or strength. The supplement combines zinc and magnesium, both linked to hormone regulation.
When either of these micronutrients drops too low, the body struggles to produce and manage hormones, including testosterone. For those with a deficiency, this can lead to low hormone levels, fatigue, and slower recovery.
Zinc supports the production of total and free testosterone. Magnesium influences how the body handles stress and sleep, which impacts hormone function.
A study looked at the effect of magnesium supplements on testosterone in both sedentary men and taekwondo athletes. Participants received magnesium for four weeks, and their serum testosterone levels were measured at rest and after physical exhaustion.
The results concluded that both free testosterone and total testosterone increased after supplements. Athletes showed a significant increase than sedentary subjects, suggesting that magnesium supports testosterone production, especially when combined with regular training.
This supports the idea that zinc and magnesium levels matter more than we realize. When someone trains hard, sweats often, or faces long-term stress, they require more zinc and magnesium. ZMA won't push hormones beyond the body's natural limit, but it may help restore balance in those running low.
The Role of Zinc in Body Functions
Zinc supports several vital functions in the body. Although only needed in small amounts, it influences health in meaningful ways.
One important role of zinc is maintaining a strong immune system. It improves white blood cell activity and modulates the body's immune response to infections. When zinc levels drop too low, the immune system may not react as quickly or effectively to viruses, bacteria, or inflammation.
Additionally, zinc deficiency is especially critical during stress, illness, or recovery. People with low zinc levels can experience longer colds or more frequent infections. It also helps metabolism by supporting the enzymes that convert food into energy and break down carbohydrates and proteins, which allows the body to use nutrients efficiently.
Without enough zinc, the body may feel sluggish or have trouble recovering after physical activity. ZMA has become a well-known dietary supplement in the world of sports nutrition. It supports physical recovery, hormonal balance, and energy production.
For athletes and individuals doing regular resistance training, ZMA often supports muscle function, strength, and faster recovery between workouts. It is known to improve body composition without the use of synthetic enhancers.
In addition to immunity and metabolism, ZMA supports building muscle mass by improving sleep quality, supporting immune health, and maintaining healthy muscle and nerve function. Zinc helps support protein synthesis, while magnesium helps muscles relax and recover after intense activity.
Steroid Hormone Metabolites and ZMA
ZMA combines zinc, magnesium, and vitamin B6. It's often marketed for its potential to support recovery, strength, and hormone regulation. One area of interest is how ZMA might affect steroid hormone metabolites, including serum testosterone.
Research on this topic shows mixed results. A study tested ZMA on 42 resistance-trained men over 8 weeks. Participants took either ZMA or a placebo while following a structured strength-training program. The researchers tracked hormone levels, body composition, and training performance.
The results demonstrated no significant changes in testosterone, IGF-1, growth hormone, or cortisol between the ZMA and placebo groups. Muscle strength and endurance also remain unchanged. This study suggested that ZMA may not affect well-trained individuals' hormone metabolism or physical performance.
However, some studies tell a different story. A study focused on NCAA football players over 8 weeks of training. The group taking ZMA experienced a 30% increase in free testosterone and an 11% boost in total testosterone, while the placebo group saw a decline.
These results suggest that ZMA may benefit steroid hormone metabolism under certain conditions, possibly when athletes have higher physical stress or borderline nutrient deficiencies. But why the difference?
Individual baseline nutrient levels could matter. Zinc and magnesium deficiencies are more common than many realize, especially in athletes. When the body lacks these nutrients, hormone production and metabolism can suffer.
ZMA may not change everyone's hormone levels. However, in cases of deficiency, ZMA supplements could restore balance and improve overall hormone function. Until more large-scale studies are done, ZMA remains a supplement worth considering, but not one to rely on as a guaranteed hormone booster.
How Much ZMA Is Too Much? Safe Dosage
ZMA supplements have become common among men looking to improve recovery, sleep, and gym performance. They contain zinc, magnesium, and vitamin B6. These ingredients help with energy and muscle health and boost testosterone. But taking ZMA properly and knowing when to avoid it is just as important.
Best Time for Taking ZMA
ZMA supplements are typically taken on an empty stomach about 30-60 minutes before bed. This way, minerals, especially magnesium, can be better absorbed in your body and improve sleep quality. Taking ZMA with food, especially foods high in calcium, can reduce how well your body absorbs zinc and magnesium. To get the most benefits, follow the recommended timing for taking ZMA.
Recommended Dosage and Mineral Balance
The recommended dosage for ZMA supplements is around 30 mg of zinc, 450 mg of magnesium, and 10.5 mg of vitamin B6. These levels are close to daily needs for healthy men and aim to fill nutritional gaps without going overboard.
However, not all products follow this standard. Some versions may include high doses that exceed the body's requirements. Taking more doesn't necessarily lead to better results. In fact, too much zinc can interfere with copper absorption and cause nausea or a weakened immune response over time.
Safety Considerations and When to Avoid ZMA
ZMA is usually safe when used as directed. However, problems can arise when people take high doses or use multiple supplements that contain the same minerals. For example, combining a multivitamin with ZMA can increase the risk of exceeding safe intake levels.
Men with kidney issues, gastrointestinal problems, or those already taking medications that affect mineral balance should avoid ZMA or talk to a healthcare provider before use.
If you're wondering, "Do zinc and magnesium boost testosterone levels?" the answer is: it depends. While these minerals support hormone health, especially when someone is deficient, ZMA does not guarantee a rise in total testosterone levels.
Some of the effects related to ZMA use may be more about correcting deficiencies than boosting hormones beyond normal levels.

Potential Risks and Side Effects of ZMA
ZMA is a popular nutritional supplement that supports recovery and hormone balance. While generally safe, it's not risk-free. Some people may experience unwanted effects related to dosage or medication interactions.
One concern involves proton pump inhibitors, which are often prescribed for acid reflux. These medications can reduce stomach acid, which affects how minerals like zinc and magnesium are absorbed. Poor absorption can reduce the effectiveness of ZMA or contribute to a nutritional deficiency over time. People taking proton pump inhibitors should speak with a healthcare provider before using ZMA.
High doses of zinc and magnesium can also cause side effects. Nausea, upset stomach, and diarrhea are possible when these minerals are taken in excess. Over time, too much zinc can interfere with copper absorption, which may lead to other health issues.
There are also concerns about how ZMA might influence inflammatory markers. Some users report changes in energy, mood, or digestion.
ZMA may also increase urinary excretion of certain compounds, though the long-term effects are not fully understood. If you have low testosterone levels, it's crucial to set realistic expectations. While ZMA may have some benefits, it is not a solution for hormonal issues and may not address the root cause of your concerns.
As with any nutritional supplement, the best approach is to scrutinize your current health, medications, and goals. Always consult a registered dietitian if you're unsure whether ZMA is a good fit.
ZMA vs. Other Testosterone-Boosting Supplements
ZMA is a natural way to support testosterone levels. But when compared to other testosterone-boosting options, ZMA may have limitations.
Many men take zinc supplements alone, especially when bloodwork shows low zinc levels. Zinc is tied to testosterone production, but more zinc doesn't always mean higher testosterone. In men without a deficiency, extra zinc may offer little benefit.
Other supplements go beyond minerals. Some include herbal extracts like ashwagandha or fenugreek. These products claim broader hormone support, but the outcomes vary based on various factors. For men with consistently low testosterone levels, lifestyle changes or over-the-counter products might not be enough. In these cases, Male Excel offers testosterone therapy, precisely tailored to your lab results..
ZMA is a good option for men looking to support recovery or close small nutritional gaps. However, it should not be viewed as a replacement for proper testing or guided treatment.
Final Thoughts
ZMA may benefit healthy men looking to support recovery, sleep, or nutrient intake.
As a supplement containing zinc, magnesium, and vitamin B6, it targets nutrients that support various body functions, including testosterone production. However, the actual impact on testosterone levels is still unclear, and more research is needed.
Some men may notice minor improvements, especially if they have a mild nutritional deficiency. However, those with normal nutrient levels may not see significant changes. Working with a registered dietitian can help you decide if ZMA fits your health goals.
If you're dealing with low testosterone symptoms and need more than basic support, consider a medical-grade approach. Male Excel offers personalized testosterone therapy, backed by lab testing and expert care. So, what are you waiting for? Take the first step towards a healthy lifestyle through guided medical treatment.
References
1. Cinar, V., Polat, Y., Baltaci, A. K., & Mogulkoc, R. (2010). Effects of Magnesium Supplementation on Testosterone Levels of Athletes and Sedentary Subjects at Rest and after Exhaustion. Biological Trace Element Research, 140(1), 18-23. https://doi.org/10.1007/s12011-010-8676-3
2. Wilborn, C.D., Kerksick, C.M., Campbell, B.I. et al. Effects of Zinc Magnesium Aspartate (ZMA) Supplementation on Training Adaptations and Markers of Anabolism and Catabolism. J Int Soc Sports Nutr 1, 12 (2004). https://doi.org/10.1186/1550-2783-1-2-12
3. Brilla, L. & Conte, V.. (2000). Effects of a novel zinc-magnesium formulation on hormones and strength. Journal of Exercise Physiology Online. 3. 26-36.